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FILE - In this Saturday Dec. 8, 2012 file photo, Egyptian TV host Bassem Youssef addresses attendants at a gala dinner party in Cairo, Egypt. Egypt?s state news agency said Saturday, March 30, 2013 that the public prosecution office has issued an arrest warrant against a popular TV satirist for allegedly insulting Islam and the country?s president. The warrant issued Saturday is the latest in a series of legal action against Youssef, known as Egypt?s Jon Stewart. The warrant comes amid a widening crackdown against opposition figures, driving fears over freedoms of expression and assembly. (AP Photo/Ahmed Omar, File)

CAIRO (AP) ? Egypt's state prosecutors ordered the arrest Saturday of a popular television satirist for allegedly insulting Islam and the country's leader, in a move that government opponents say is aimed at silencing critics of Islamist President Mohammed Morsi.

The arrest warrant for against Bassem Youssef, who has come to be known as Egypt's Jon Stewart, followed an order earlier this week by the country's top prosecutor to arrest five prominent pro-democracy activists in what the opposition has characterized as a widening campaign against dissent.

The acceleration in legal action targeting protesters, activists and critics comes against a backdrop of continued unrest in the country. Political compromise between the well-organized Islamists in power and their vocal liberal and largely secular critics remains elusive, while the country's economy is in near free fall, which has increasingly fueled popular frustration.

The opposition charges that Morsi, in office for nine months, and the Brotherhood have failed to tackle any of the nation's most pressing problems and are trying to monopolize power, breaking their promises of inclusiveness. Morsi blames the country's woes on nearly three decades of corruption under his predecessor, Hosni Mubarak, and accuses the opposition of stoking unrest for political gain.

The warrant against Youssef is the latest in a series of legal actions against the comedian, whose widely-watched weekly show, "ElBernameg" or "The Program," has become a platform for lampooning the government, opposition, media and clerics. He has also used his program to fact-check politicians.

The fast-paced show has attracted a wide viewership, while at the same time earning itself its fair share of detractors. Youssef has been a frequent target of lawsuits, most of them brought by Islamist lawyers who have accused him of "corrupting morals" or violating "religious principles."

Prosecutor Mohammed el-Sayed Khalifa told Al-Ahram online that he has heard 28 plaintiffs accusing Youssef of insulting Islam, mocking prayers, and "belittling" Morsi in the eyes of the world and his own people.

In one episode of the show, Youssef mocks former militants who are now part of the mainstream political scene in Egypt. At a recent rally, some former radicals who were imprisoned for taking part in the assassination of late President Anwar Sadat in 1981, accused the opposition of using violence at anti-Morsi protests.

In the program, Youssef ridicules an Islamist who said the militants had repented by fasting for three months for mistakenly killing others with Sadat.

"What a message," Youssef says. "Anyone can form a group in the name of religion, assassinate in the name of religion, and then oops! Repent and fast for three months, and it will too pass in the name of religion."

The comedian has faced several court cases in the past accusing him of insulting Morsi. One of Youssef's attorneys, Gamal Eid, said however that this is the first time an arrest warrant has been issued for the comedian.

In a post on his official Twitter account, Youssef said he will hand himself in to the prosecutor's office Sunday. He then added, with his typical sarcasm: "Unless they kindly send a police van today and save me the transportation hassle."

Eid said the warrant fits into a widening campaign against government critics, media personalities, and activists, saying "the prosecution has become a tool to go after the regime's opposition and intimidate it."

A call to a top aide to the country's chief prosecutor, Hassan Yassin, for comment went unanswered.

The other recent arrest warrants for five high-profile activists were issued over allegations that they instigated violence last week near the Brotherhood's headquarters in Cairo, where nearly 200 people were injured in clashes between anti-government protesters and supporters of the Brotherhood, from which Morsi hails.

Morsi responded by harshly criticizing his opponents, calling them hired thugs out to derail Egypt's democracy. The Brotherhood also blamed privately-owned media for fanning the violence.

The criticism was followed by a two-day protest by dozens of Islamists outside the studios of TV networks critical of Morsi. The protesters pelted police and prevented some talk show hosts and guests from entering or leaving the complex.

The New York-based Committee to Protect Journalists called the escalation of anti-press "rhetoric" by Morsi and his supporters and the sit-in outside the media city were "deeply troubling."

The series of prosecutions and arrest warrants come amid a legal challenge to the chief prosecutor, Talaat Abdullah, whose appointment by Morsi last year was declared void by a court ruling earlier this week.

On Saturday, Abdullah said he will appeal the court ruling, saying it is "in violation of the constitution and the law," Egypt's state news agency reported. The decision signals a protracted legal battle is likely to ensue, further confusing the legal scene in Egypt.

In the Mediterranean port city of Alexandria, an Egyptian rights group said Saturday that police detained 13 people, including five lawyers, and accused them of assaulting police. The arrests inside the police station mark a rare instance in which lawyers face potential criminal charges.

The Haqanya Center for Rights said the 13 are accused of insulting security officials, attempting to free other detainees at the police station and illegal assembly.

The arrests prompted an angry response from lawyers at Cairo's Bar Association, who demanded an apology from the police.

Those detained include prominent lawyer and pro-democracy activist Mahienour el-Masry. Several dozen Cairo protesters held a rally outside the chief prosecutor's office, dismissing his orders as void, locking up the gates to his office with chains and demanding the release of the lawyers and activists.

Mohammed Abdel-Aziz, an attorney, said the lawyers and activists were beaten and assaulted at the station, where they had been since Friday to represent three opposition members reportedly detained and taken to the police by members of a political party affiliated with the Brotherhood.

Associated Press

Source: http://hosted2.ap.org/APDEFAULT/cae69a7523db45408eeb2b3a98c0c9c5/Article_2013-03-30-Egypt/id-f27c3adb09624ad6892b128d6654ec0c

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syfvuali · Mar. 28, 2013

Mar. 28, 2013 ? Hybrid offspring of different house mice populations show a preference for mating with individuals from their father's original population.

Mate choice is a key factor in the evolution of new animal species. The choice of a specific mate can decisively influence the evolutionary development of a species. In mice, the attractiveness of a potential mate is conveyed by scent cues and ultrasonic vocalizations. Researchers from the Max Planck Institute for Evolutionary Biology in Pl?n investigated whether house mice (Mus musculus) would mate with each other even if they were from two populations which had been separated from each other for a long time period. To do this, the researchers brought together mice from a German population and mice from a French population. Although to begin with all the mice mated with one another randomly, the hybrid offspring of French and German parents were distinctly more choosy: they showed a definite preference for mating with individuals from their father's original population. According to the researchers, this paternal imprinting accelerates the divergence of two house mouse populations and thus promotes speciation.

In allopatric speciation, individuals of a species become geographically isolated from each other by external factors such as mountains or estuaries. Over time, this geographic separation leads to the sub-populations undergoing various mutations, and thus diverging genetically. Animals from the two different sub-populations can no longer successfully reproduce, so two new species evolve.

To find out what role partner selection plays in such speciation processes, Diethard Tautz from the Max Planck Institutefor Evolutionary Biology and his colleagues conducted a comprehensive study on house mice -- the classic model organisms of biology. "To investigate whether there are differences in the mating behaviour of the mice in the early stages of speciation, we caught wild house mice in southern France and western Germany. The two populations have been geographically separate for around 3,000 years, which equates to some 18,000 generations," says Diethard Tautz. Due to this geographical separation, the French and German mice were genetically different.

The Pl?n-based researchers created a semi-natural environment for their investigations -- a sort of "Playboy Mansion" for mice. The research enclosure was several square meters in size and was divided up using wooden walls, "nests" made out of plastic cylinders, and plastic tubes. It also featured an escape tube with several entrances, which led into a cage system nearby. "We constructed the enclosure in such a way that all animals had unimpeded access to all areas, but thanks to the structural divisions were also able to create their own territories or retreat into nests," explains Tautz. "The escape tube was a control element. If the mice retreated to it only very seldom -- as was the case in our experiment -- then we could be sure there was no overpopulation in the central enclosure."

In this central enclosure, the French and German mice had both time and space to mate with each other and reproduce. "At first, all the mice mated with each other quite randomly. But with the first-generation offspring, a surprising pattern emerged," says Tautz. When the first-generation hybrid offspring of mixed French and German parentage mated, they showed a specific preference for pure-bred mates whose "nationality" was that of their father only. "There must be some kind of paternal influence that prompts the hybrid mice to choose a mate from a specific population, namely that of their father," concludes the biologist, based on the results of his study. "This imprinting must be learned, however, meaning that the animals must grow up in the presence of their fathers. This was not the case for the original mice, which were kept in cages for a time after being caught."

"We know that mice use ultrasonic vocalizations to communicate with each other and that particularly in the case of male mice these vocalizations can reveal signals of individuality and kinship. We believe that, like birdsong, the vocalizations of the males have a learned component and a genetic component," says Tautz. Therefore, French and German mice really could "speak" different languages, partly learned from their fathers, partly inherited from them. Individual mice thus have a mating preference for mice that speak the same language as they do.

The French and German mouse populations had evidently been geographically separated long enough for preliminary signs of species differentiation to be apparent as regards mating preferences. In addition, another aspect of mating behavior also sped up the speciation process. Although mice have multiple mates, the researchers found evidence of partner fidelity and inbreeding. The tendency to mate with relatives fosters the creation of genetically uniform groups. When both occur together, this accelerates the speciation process.

In a next step, Diethard Tautz wants to find out whether the vocalizations of the mice play the decisive role in paternal imprinting, or if scent cues are also involved. Furthermore, the biologist wants to identify the genes that are involved in mate selection.

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The above story is reprinted from materials provided by Max-Planck-Gesellschaft.

Note: Materials may be edited for content and length. For further information, please contact the source cited above.

Journal Reference:

Inka Montero, Meike Tesche and Diethard Tautz. Paternal imprinting of mating preferences between natural populations of house mice (Mus musculus domesticus). Molecular Ecology, 2013 DOI: 10.111/mec.122271

Note: If no author is given, the source is cited instead.

Disclaimer: Views expressed in this article do not necessarily reflect those of ScienceDaily or its staff.

Source: http://feeds.sciencedaily.com/~r/sciencedaily/most_popular/~3/oUt1DL9X6YE/130328125331.htm

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Many people do not take advantage of having the opportunity to travel because there are so many details to consider. Learning the best methods to traveling is going to help you in opening the many doors that are presented to you, from traveling to so many great places around the world.

One decision you need to make when taking a trip is whether to buy travel insurance at all. If you are flying to New York and the ticket only costs $150, it's not really worth paying another $50 to cover that trip in case of cancellation. However, if you are taking the trip of your dreams to a faraway place, it might be well worth the incremental expense on a $4,000 vacation to know that your money won't be lost in the event of a cancellation.

If you are traveling with a companion but you do not normally share funds, consider having a joint wallet, for expenses like meals, travel and lodging. You and your companion can add the same amount of money to the joint wallet each day. This way, you aren't constantly splitting bills or exchanging money.

When you are packing, try to develop a system that facilitates where each of your items will be stored. This will help you to pack in an efficient manner so that you can reduce the stress of getting ready and save valuable time. Stay organized to maximize your packing experience.

When traveling to a foreign country, avoid dressing in a way that marks you as a wealthy tourist. Wear normal, casual clothing and don't wear expensive watches, jewelry, cameras, and other things that can call attention to you. Try not to bring a lot of things with you during the day, in order to avoid having your things lost or stolen.

Children are not always the best travelers. If you will keep them busy, they will be much happier while traveling by car or plane. Pack a bag of activities for your child to do while traveling. Pick things that they like to do, things that they do not commonly get. Get them a new coloring book or a new book to read.

When traveling internationally with disabilities it is best to check which countries best accommodate disabled citizens. Many countries are well equipped to offer travelers with wheel chair ramps, scooter ramps and have hotels that are equipped to deal with disabilities. Unfortunately, every country is not so well equipped to support travelers with disabilities.

If you are going to be traveling on an airplane, purchase some antibiotic ointment and cotton swabs. Before you leave to catch your flight, put a generous amount of the ointment on the inside of your nose. It keeps out the germs and helps prevent you from getting sick. It also keeps your nose from drying out.

If you are traveling with any battery operated devices in your suitcase, turn the batteries around. This will prevent the batteries from being wasted, if your item is accidentally turned on. Just be sure to turn the batteries back around when you unpack, or you might think the item is broken!

Drive through windows at fast food places almost inevitably give you too much or too little sugar or other sweetener when you order coffee or tea. When traveling, don't throw the extra away! Tuck into a baggie or maybe a little tin and keep it for the next time you are shorted. It sure beats having to turn around and go back through the drive through!

If you are traveling to a known destination with a responsible party on the other end, consider shipping your luggage ahead of time. With new luggage fees from virtually all major airlines, the cost will often be the same or less than checking it on the flight with you. In addition, you will have the luxury of traveling with comfort and ease, without the stress of standing in luggage lines, tipping porters, and the worry of lost luggage.

You need to keep your passport secure when you travel. There are people who will steal a passport if they see it so that they can sell it to someone illegally. The only way to avoid this type of theft is to keep up with your passport at all times when you are traveling.

When traveling to a foreign country, try using public transportation. Many countries have exceptional railway and subway systems, better than anything in the U.S.A. Public transportation is usually inexpensive and you will never have to worry about getting lost on a lonely road. Just be cautious of pick pockets when you board the bus or train.

If you are traveling to a country that may have people hostel to American citizens try to blend in. Do not draw attention to yourself by wearing clothing that may give away the fact that you are an American. It is much safer for people to think you are a Canadian or European.

Try to avoid jet lag during your trips by following these simple things. Start by resetting your watch before boarding your plane. Make sure that you stay incredibly hydrated before, during and after the flight. Try exercising and sleeping well days before your trip. Fly on morning flights if you cannot sleep on a plane. Seek and avoid light as you need it until your body adjust to the time differences.

Create an impromptu humidifier, using a bottle of water and a handkerchief or small towel. Airplane cabins are notorious for their dry air, which can irritate your lungs and sinuses. If the dryness starts to bother you, moisten a small towel with a bit of water and lay it across your nose and mouth. Lean back and as you breathe, the water in the towel will hydrate the air you inhale.

If you need to travel across the country but are on a limited budget, consider traveling by bus. In the past, bus travel was viewed somewhat unfavorably, but today major players like Greyhound, have made major improvements to attract the growing number of travelers who can't afford plane tickets. Today bus lines are a more civil experience. Cleaner, newer buses are the norm and most stations offer free wireless internet access and sundries.

Cruise ships offer plenty to do on-board, with the option of exploring off the ship when you dock. Apply the tips from this article to make the most of your next cruise.

Source: http://travel-leisure-blogs.blogspot.com/2013/03/amazing-travel-tips-just-for-you.html

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By Ree Hines, TODAY contributor

Bravo bigwig Andy Cohen launched the network's ever-growing, always-popular franchise, "The Real Housewives," in 2006. What started with a few privileged, entertaining and often-argumentative women from the O.C., eventually expanded to include the dozens of frequent feuders from coast to coast.

On Friday morning, Cohen visited TODAY and fielded a couple of questions about the leading ladies on the shows -- questions that he wasn't exactly eager to answer.

For instance, which Housewife is his personal favorite?

"That is horrible! That is a terrible question," he said with a smile as he mulled it over. "I would get in terrible trouble. ... I love when any of them really succeed."

And that means he's really loving one woman right now.

"You know, NeNe Leakes is going through a major period of success -- from, of course, 'The Real Housewives of Atlanta,'" he shared. "She's got a starring role in 'The New Normal' on NBC. I'm especially proud of her right now."

There's even more for Cohen to be proud of where Leakes is concerned.

After several years of fussing and fighting, Leakes and her former "Real Housewives of Atlanta" co-star Kim Zolciak have finally buried the hatchet and gone back to being BFFs, a fact Leakes recently celebrated on Twitter.

As for Cohen, if he was a little reluctant to name his favorite Housewife, that's nothing compared to his reaction when asked to name his least favorite.

"Oh, yes! Let me tell everybody about it," he joked. "Yes! Let me rank my top five least favorite Housewives for you right now. No! Love them all for different reasons."

See more from Cohen on part two of "The Real Housewives of Beverly Hills" reunion special Monday night, or see him on his own show, "Watch What Happens Live," which airs Sunday through Thursday nights -- both on Bravo.

Who's your favorite or least favorite Housewife? Share your thoughts on our Facebook page.

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Source: http://theclicker.today.com/_news/2013/03/29/17517004-andy-cohens-favorite-real-housewives-star-nene-leakes-at-least-for-now?lite

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Source: http://www.thehollywoodgossip.com/2013/03/khloe-kardashian-pregnant-tabloid-claims-slash-asks-who-is-the-f/

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By Toni Clarke

WASHINGTON (Reuters) - U.S. regulators on Wednesday approved a new multiple sclerosis drug made by Biogen Idec Inc that is widely expected to become the No. 1 oral treatment for the disease, with annual sales topping $3 billion.

The drug, Tecfidera, activates a chemical pathway in the body known as Nrf2 that helps protect nerve cells from damage and inflammation. Following Wednesday's approval by the Food and Drug Administration, Biogen said it will launch the drug within the coming days.

Multiple sclerosis is a chronic condition that attacks the central nervous system and can lead to numbness, weakness, paralysis and blindness. It affects more than 2.1 million people worldwide, according to the National Multiple Sclerosis Society.

"We expect a solid launch of Tecfidera, and our sense is that there is a bolus of patients in the queue ready to transition to therapy," Geoff Meacham, an analyst at J.P. Morgan, said in a research note. "However, we believe that Street expectations likely already account for this and then some."

Shares of Weston, Massachusetts-based Biogen rose 3.2 percent to close at $182.68 on Wednesday. The shares have more than tripled over the past three years, mainly driven by high hopes for Tecfidera, known chemically as dimethyl fumarate.

Biogen already sells the MS drugs Avonex and Tysabri, which together account for about 30 percent of the market. Teva Pharmaceutical Industries Ltd's drug Copaxone is the current market leader, with a roughly 29 percent share and annual sales last year of more than $4 billion.

Unlike Copaxone, Avonex and Tysabri, which are injected or infused, Tecfidera comes in the more convenient form of a pill. As such, it will compete with Novartis AG's MS pill Gilenya, which, though first to market, has been dogged by heart safety concerns. Gilenya holds an 8.5 percent share of the market and generated worldwide sales of $1.2 billion last year.

Tecfidera will also compete with Sanofi's recently approved MS pill Aubagio. Aubagio's label carries a boxed warning -- the most serious kind of warning -- alerting physicians to a potentially heightened risk of liver problems.

Novartis said in a statement that it welcomed additional treatment options for people with MS, but warned that Tecfidera may not perform as well in the market as in clinical trials.

"As with any new medication, real-world experience is critical to gain an accurate understanding of a therapy's full clinical profile," the company said. "It will be important to see the clinical profile of dimethyl fumarate -- including efficacy, safety, tolerability and adherence with its twice-a-day dosing -- as it gains real-world experience."

Michael Yee, an analyst at RBC Capital Markets, said the overall profile of Tecfidera looks "significantly better than Gilenya."

Tecfidera's side effects appear relatively benign, consisting mainly of flushing, diarrhea and nausea. And its label contains no boxed warnings. The FDA recommended only that physicians monitor patients' infection-fighting white blood cell count once a year.

"That's an excellent label," said Yee. "I expect the drug to meet consensus of $300 million this year, and over five years it can achieve greater than $3 billion in sales based on its convenience and efficacy profile."

Tecfidera will be used to treat patients with relapsing-remitting MS, a form of the disease in which flare-ups are followed by periods of remission. About 85 percent of people with MS are initially diagnosed with this form of the disease.

Combined clinical trial data showed Tecfidera cut the average relapse rate by 49 percent after two years compared to patients taking a placebo. The drug is expected to generate sales of about $3 billion in 2017, according to data compiled by Thomson Reuters Cortellis.

Last week European regulators recommended approval for Tecfidera and Aubagio, but they declined to give Aubagio a "new active substance" designation because it is similar to an older drug. Without this designation, generic copies of the drug could be launched in Europe in as little as three years. That could hurt sales of most other MS drugs on the market.

Sanofi said it was disappointed by the decision and plans to request a re-examination of the case.

(Reporting By Toni Clarke in Washington; additional reporting by Bill Berkrot in New York; Editing by Tim Dobbyn, Bernard Orr and Leslie Adler)

Source: http://news.yahoo.com/fda-approves-biogens-oral-ms-drug-tecfidera-211006120--finance.html

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If you think ?copywriting? (writing words that persuade people to do or buy something) is only about creating ads, you?re missing the point. Copywriting is a skill has created more six-figure incomes than you might imagine. In some cases, seven-figure incomes.

Type writer

For instance, one of my best friends generates a healthy $150,000 per month from his home-based business, and at its core, that business is fueled by my friend?s copywriting skill.

If you truly want to start your own business, or create a second income stream, one of the first things I would recommend you learn is the basic skill of powerful copywriting.

Now, this is not some ?get rich quick? scheme?

This is a serious business skill than can provide you with a comfortable six-figure annual income for the rest of your life.

You can run your business from anywhere. You can dream up promotions and campaigns, write the copy, and put the plan into profit? all in the same day.

And yes, you could ?retire? from your present job, and use your copywriting skills to build your own marketing empire?- working wherever and whenever you want.

I have run my business from all over the USA, Canada, Mexico, the Caribbean, and the UK:

Working form home in the Northwest US (sometimes at my house, sometimes from my office 5 minutes away, and sometimes from Starbucks!)?
On the road in my motorhome (summer-before-last we put 8,000 miles on the coach, the last winter we spent in California)?
Traveling to Chicago, San Diego, Los Angeles, Seattle, Toronto and New York?
On vacation with family in Michigan, the Carolinas, Utah, and Montana?
And from England and Scotland?

My results are not typical?- you?ll have your own results. Want to join me in the ?not typical? club? Want to know how I managed to get these unusual results?

It comes down to one skill: copywriting. Now, ask yourself? if you learned how to master the art of ?persuasion in print?, how could that change your life?

Will you finally get your online business started?
Will you write copy freelance, and live a life free from offices, meetings, and memos?
Will you take your existing online business and multiply your profits using the power of copy?

Or will you keep struggling along like most ?Internet Marketers?? That road leads nowhere. You don?t need to learn the new ?shiny object of the week? system. You don?t need the latest greatest website.? You just need a skill that is valued, and that has the power to give you leverage. The skill I recommend starting with is the ability to write persuasive copy.

If you have decided that I am right about this, give life to that decision and do something about it. Pick up a book, take a copywriting course, or just sit down and write a piece of copy. Today. Maybe even right now.

A good place to start would be with my book on copywriting. An even better place to start would be with the live webinar training about copywriting I?m doing next Tuesday.

Question: How can you profitably apply the power of persuasive copy in your business?

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packaging technology

Saturday, March 30, 2013

Egypt issues arrest warrant for TV satirist

Mate choice in mice is heavily influenced by paternal cues, mouse study shows

Travel & Leisure Blog's: Amazing Travel Tips Just For You

Friday, March 29, 2013

Cohen's favorite Housewife? NeNe -- for now

Thursday, March 28, 2013

Khloe Kardashian Pregnant, Tabloid Claims/Asks: Who is the Father?!?

FDA approves Biogen's oral MS drug, Tecfidera

How Copywriting Creates Six-Figure Incomes | Ray Edwards